Department of Pharmacology and Toxicology
Scientific research activity
Institute of Pharmacology
The Institute of Pharmacology solves the project VEGA focused on effect of natural humic substances as feed additive on health status, immune system, production parameters and meat quality of broiler chicken. Besides that, members of institute participate on APVV project (APVV-15-0377) aimed of biofilm formation and resistance in genus of Malassezia yeasts.
- VEGA 1/0408/17: The effect of humic acid on health, production parameters and meat quality of broiler chicken, period of solution: 2017 – 2019.
Institute of Toxicology
The field of research in the Institute is to determine the direct toxicity of plant protection products, pharmaceuticals and environmental contaminants to animals and humans using different animal models or in vitro models. The effects of low doses of pesticides, pharmaceuticals, pharmaceuticals and animal poisons in their long-term (chronic) effects on the animal organism, mainly to determine their risk of immunotoxicity, hepatotoxicity, genotoxicity, embryotoxicity in humans, animals, wild animals, fish and bees are studied.
- European Commission - Annex Inclusion Renewal (AIR) I. II. III. Ecotoxicological risk assessment of selected pesticide active ingredients (Prohexion-calcium AIR I, Prosulfuron AIR II, Glyphosate AIR II, Foramsulfuron AIR III).
- VEGA 1/0858/16: The negative impact of selected xenobiotics at the larval stage of the honey bee.
- VEGA 1/0287/11: Ecotoxicological studies and genotoxic xenobiotics on non-target organisms.
- VEGA 1/0393/2008: Monitoring the interactions of selected pesticidesand heavy metals in Artemia franciscana.
- Phare SK 2005/IB/AG/02-TL,2005 – 2006: Twinning Light, Further Strengthening of Systems for Registration and Plant Protection Products between UK and Slovakia.
- VEGA 2/7026/20:2000-2003/SAV Košice: Biotransformation of environmental contaminants by organism of animals.
Institute of Human and Clinical Pharmacology
Two main research topics of IHCP are: 1) The pharmacological influence on the central regulation of food intake, and 2) The antitumor effect of substances isolated from natural sources. Both of them are solved under close scientific collaboration with external scientific institutions.
- VEGA 1/0103/16: Brasinin and its derivatives as potential anti-cancer drugs, implementation 2016 – 2018.