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Organisation structure

Department of microbiology and immunology

Diploma theses

Institute of microbiology and gnotobiology

General veterinary medicine - diploma thesis:
  • Bacterial infections of urinary tract in dogs and cats
  • Replication of Tribeč virus in cell cultures of human and animal origin
  • Molecular-biology diagnostics methods for detection and characterization of Campylobacter spp.
  • PCR detection of selected viral pathogens in wild boar (Sus scrofa) from Slovakia
  • Usutu virus (genus Flavivirus) in the avifuana of wetland ecosystem of Drienov
  • Tick-borne arboviruses in free living rodents
  • Tribeč virus (genus Orbivirus, Great Island virus serogroup) in birds and livestock animals in Slovakia
  • Prevalence of Staphylococcus aureus as important causal agent of mastitis in milk of dairy cows
  • Incidence of pyoderma in dogs according to the breed and age of the animal
  • Feline urinary tract infections and their treatment
Pharmacy:
  • In vitro study of the effect of natural substances on the biofilm production by pathogens
  • Selected in vitro methods for determination of antibacterial activity of essential oils
Doctoral thesis:
  • Surviving of production probiotic strains in selected application form
  • Postantibiotic colitis in hospital environment
  • Gastrointestinal infections of bacterial origin, the possibilities of their therapy and protective effects of probiotics
PhD thesis:
  • Species diversity and characterisation of arboviruses and their vectors
  • Characterization of biological properties of arboviruses with occurence in Slovakia
  • Syndrome of neuroinvasive zoonoses in relationship to antigenic diversity and differential diagnostic
  • Characteristics of immunopharmacological effect of chemicals with potentiated effect on probiotics

Laboratory of gnotobiology

General veterinary medicine – diploma thesis:
  • The study of Gram positive cariogenic bacteria isolated from dental biofilm
  • The study of bioactive substances in selected dental biofilm bacteria
  • The use of gnotobiotic laboratory animals in the study of inflammatory bowel diseases
Pharmacy:
  • Antibiofilm potential of biosurfactants isolated from marine bacteria
  • In vitro study of the properties of beneficial bacteria intended for harmonization of the natural microbiocenosis of the skin
  • The influence of probiotic bacteria stabilised on alginite and its humic extracts on intestinal and overall metabolism of model laboratory animals
  • Use of germ-free animal models in biomedical research
Doctoral thesis:
  • Microbiological analysis of oral microflora from the perspective of dentistry in the veterinary and human medicine
  • Antimicrobial and antibiofilm potential of bioactive products of beneficial microorganisms against multi-drug-resistant pathogens

Institute of immunology

General veterinary medicine – diploma thesis:
  • Effect of exopolysaccharides isolated from L. reuteri on the ability of salmonella to adhere and invade IPEC-1 cells
  • Selection of probiotic bacteria for bees
  • Effect of humic acid application on the cellular immune response of poultry
  • Effect of the Lactobacillus reuteri probiotic strain on the cellular immune response of mice infected with enterotoxigenic E. coli
  • Diagnostics of atopy in dogs
  • Effect of probiotic bacteria on the activity of phagocytes in dogs
Pharmacy:
  • Influence of application of bioproducts on the cellular immune response of poultry
Doctoral thesis:
  • Assessment of adverse effects in modulating the immune response in patients with Crohn's disease
  • Immunological aspects of rheumatoid arthritis
  • Study of the effect of the combination of 5-fluorouracil and Immodine on the immune response of mice with colorectal carcinoma
PhD thesis:
  • In vitro study of immunomodulatory effect of exopolysaccharides Lactobacillus reuteri
  • Immunomodulators of natural origin in fish and bee farms
  • Study of the effect of substances of natural origin with immunomodulatory effect on the model organism
  • Health aspects of the use of probiotics in veterinary medicine

Laboratory of biomedical microbiology and immunology

PhD thesis:
  • Development of protein arrays for identification of the various infections
  • Study of protein interactions between cells of neurovascular unit and neuroinvasive pathogens and its role in the neuropathogenesis
  • Development of songle domain antibody fragments (nanobodies) against neuroinvasive Neisseria
  • Analysis of ligand-receptor interactions between Borrelia and the cells of neurovascular unit as basis for development of antiborrelia therapeutics
  • Development and production of peptides against neurovascular pathogens