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Organisation structure

Department of Pharmacology and Toxicology

Scientific research activity

At present time are research activities of DPaT based on:

  • investigation the influence of secondary metabolites of selected lichens on angiogenesis, proliferation of tumor cells and growth of pathogenic yeasts.
  • testing the antifungal efficacy of plant essential oils and their components on yeast virulence factors
  • determination the direct toxicity of plant protection products, pharmaceuticals and environmental contaminants to animals and humans using different animal models or in vitro models.
  • investigation of effects of low doses of pesticides, pharmaceuticals, pharmaceuticals and animal poisons in their long-term (chronic) effects on the animal organism, mainly to determine their risk of immunotoxicity, hepatotoxicity, genotoxicity, embryotoxicity in humans, animals, wild animals, fish and bees are studied.
  • Investigation of the pharmacological influence on the central regulation of food intake
  • Research in the field of antitumor effect of substances isolated from natural sources.
Projects:
  • VEGA 1/0408/17: The effect of humic acid on health, production parameters and meat quality of broiler chicken, period of solution: 2017 – 2019
  • VEGA 1/0285/22 "Canine neonatal tissues as an alternative source of mesenchymal stem cells in regenerative medicine", Solution period: 2022 – 2025
  • VEGA 1/0071/21 Monitoring the influence of metabolites of selected lichens on angiogenesis, proliferation of tumor cells and growth of pathogenic yeasts.
  • Demand-oriented research for sustainable and innovative food, Drive4SIFoodNFP313010S984
  • European Commission - Annex Inclusion Renewal (AIR) III. Ecotoxicological risk assessment of selected pesticide active ingredients (boscalid AIR III, etofenprox AIR III).
  • VEGA 1-0166-2021: Effect of combined exposure to neonicotinoid insecticides and azole antifungals on selected species of non-target organisms
  • APVV-21-0185: The influence of polluted environment on the incidence of bee nosematosis
  • PERIAMAR COST Action (CA18221) PEsticide RIsk AssessMent for Amphibians and Reptiles
  • VEGA 1/0166/21 Effect of combined exposure to neonicotinoid insecticides and azole antifungals on selected species of non-target organisms
  • VEGA 1/0446/22 Study of chalcones in the context of their action on membrane transporters responsible for drug resistance
  • VEGA 2/0112/22 "High-energy grinding of egg waste based on calcite and selected plants for the preparation of nanocrystalline minerals and environmental application"